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Artane

Artane

Artane is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It is also used ...

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Eldepryl

Eldepryl

Eldepryl is used in combination with levodopa or levodopa and carbidopa combination to treat Parkinson's disease (someti...

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Generic Mirapex

Generic Mirapex

Generic Mirapex has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease. Pramipexole tablets are used to treat signs and symptoms of Parkinson's disease and for the treatment of Restless Legs Syndrome (RLS)

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Generic Symmetrel

Generic Symmetrel

Generic Symmetrel is an antiviral. It is used to prevent or treat certain influenza (flu) infections (type A). It may be given alone or along with flu shots. Generic Symmetrel will not work for colds, other types of flu or other virus infections. This medicine is also used to treat Parkinson's disease and other movement disorders.

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Generic Artane

Generic Artane

Generic Artane is used to treat Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced.

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Generic Motilium

Generic Motilium

Generic Motilium is a medicine that increases the movements or contractions of the stomach and bowel. It is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease.

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October 07, 2017

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Parkinson's disease: mechanisms and models. - NCBI - NIH

October 13, 2017. Heterozygous PINK1 p.G411S increases risk of Parkinson's disease... (https://academic.oup.com/brain/article/140/1/98/244 9753/Heterozygous-PINK1-p-G411S-increases-risk-of) 2 Nov 2016 . risk of Parkinson's disease via a dominant-negative mechanism... Parkinson's disease, PINK1, heterozygous mutation, ubiquitin, mitophagy .

October 05, 2017
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29 Aug 2017. The development of Parkinson's disease is linked to an overabundance of the protein alpha-synuclein, which is found mainly at the end of .

October 11, 2017. Parkinson Disease: Practice Essentials, Background, Anatomy (http://emedicine.medscape.com/article/1831191-overv iew) 26 Jul 2017 Parkinson disease (PD) is one of the most common neurologic disorders, affecting approximately 1% of individuals older than 60 years and .

October 14, 2017
Exploring a Novel Pathogenetic Mechanism in Parkinson's Disease... i2
Exploring a Novel Pathogenetic Mechanism in Parkinson's Disease. Rapid Response Innovation Awards, 2008. The research from this grant has continued with .

October 06, 2017
2 Oct 2017. A study recently published in the journal Neuron sheds new light on the disease- causing mechanism behind Parkinson's. Broadly speaking . i3
Parkinson's breakthrough: New disease-causing mechanism found

October 09, 2017

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Parkinson's disease | Human Molecular Genetics | Oxford Academic

October 08, 2017
Parkinson's disease is one of the several neurodegenerative disorders that affects. Blaylock RL, Maroon J. Immunoexcitotoxicity as a central mechanism in  . i5
Parkinson's disease: Microglial/macrophage-induced...

October 10, 2017
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26 Sep 2017. A KAIST research team has identified a new mechanism that causes the hallmark symptoms of Parkinson's disease, namely tremors, rigidity, .

November 06, 2017

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Research News: Parkinson's Disease Mechanism Discovered...

November 01, 2017. Biological networks in Parkinson's disease: an insight into the... (https://bmcgenomics.biomedcentral.com/articles/10.1 186/s12864-017-4098-3) 12 Sep 2017 Parkinson's disease (PD) is the second most prevalent.. Thus, our study provides important insight into the epigenetic mechanism (lncRNA, .

November 04, 2017
Our major research goal is to understand the molecular mechanisms driving the loss of brain cells in Parkinson's disease patients. i1
Molecular Mechanisms of Parkinson's Disease | Research Projects...

October 29, 2017. Inflammatory Mechanisms of Neurodegeneration in Toxin-Based... (https://www.hindawi.com/journals/pd/2011/713517/) 9 Dec 2010 Parkinson's Disease is a peer-reviewed, Open Access journal that. as several endogenous inhibitory and apoptotic mechanisms operating .

November 08, 2017
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7 Sep 2017. Northon the west Medicine scientists have identified a toxic cascade that leads to neuronal degeneration in patients with Parkinson's disease (PD), .

November 07, 2017
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Advances in the Mechanisms of Parkinson's Disease - Christopher...

October 30, 2017

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Parkinson's Disease: Mechanisms and Models - ScienceDirect

November 02, 2017
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Parkinson's disease - Wikipedia

November 09, 2017
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Abstract. As the substantia nigra degenerates in Parkinson's disease (PD), the nigrostriatal pathway is disrupted, reducing striatal dopamine and producing PD  .

November 05, 2017
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In this animation, see how the degeneration of neurons in the substantia nigra results in a decreased availability of dopamine, causing symptoms of Parkinson's  .

October 31, 2017

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Parkinson's Disease Mechanism Identified - Columbia University...

November 25, 2017

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The mechanism of sirtuin 2-mediated exacerbation of alpha - PLOS

December 04, 2017. Mechanisms of Disease: Parkinson's - MedPage Today (https://www.medpagetoday.com/resource-center/parkin sons-disease/mechanisms-of-disease/v/34700) In this animation, see how the degeneration of neurons in the substantia nigra results in a decreased availability of dopamine, causing symptoms of Parkinson's disease.

December 03, 2017
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4 Jun 2017. Researchers have identified the precise toxic mechanism at work during an overabundance of the protein alpha-synuclein in neurons—the protein is a key causative agent in the development of Parkinson's disease.

November 27, 2017
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Molecular mechanism triggering Parkinson's disease identified in...

November 30, 2017
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Researchers from Stanford University believe they have found not only a universal biomarker to detect Parkinson's in its earliest stages — they think they have also found the link between a specific genetic mutation and the mechanisms particular to the progression of the disease. Every year, some 60,000 people in the .

December 01, 2017

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Parkinson's Disease: Genetics and Pathogenesis | Annual Review...

November 28, 2017
l-DOPA's mechanism of action in Parkinson's disease: Trends in... i5
Despite the long clinical use of l-DOPA, the exact mechanism by which this drug alleviates symptoms of Parkinson's disease is far from being fully understood. The present review summarizes recent findings about the mechanism of action of l-DOPA. Special emphasis is given to the most important phenomenon that limits  .

November 26, 2017
Expert-reviewed interactive pathway providing a current overview of Dopamine Signaling in Parkinson's Disease, a pathway description, select reviews, and. Parkinson's disease is the second most prevalent neurodegenerative disorder. Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. i6
Dopamine Signaling in Parkinson's Disease Interactive Pathway | CST

December 02, 2017
17 Mar 2017. Various mechanisms have been proposed to contribute to Parkinson disease ( PD). This schematic only includes some of these mechanisms, primarily to highlight the emerging directions in PD research and the multifactorial nature of the envisioned neurodegenerative cascade. Solid arrows represent . i7
The two-century journey of Parkinson disease research | Nature...

November 24, 2017

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C-Abl and Parkinson's Disease: Mechanisms and Therapeutic...

December 28, 2017

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Structure of PINK1 and mechanisms of Parkinson's disease... - eLife

December 22, 2017
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Current understanding of the molecular mechanisms in Parkinson's...

December 30, 2017
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14 Jun 2011. α-synuclein (aS) is a natively unfolded pre-synaptic protein found in all Parkinson's disease patients as the major component of fibrillar plaques. Metal ions, and especially Cu(II), have been demonstrated to accelerate aggregation of aS into fibrillar plaques, the precursors to Lewy bodies. In this work .

December 26, 2017
Mechanisms for pattern specificity of deep-brain stimulation in... i3
16 Aug 2017. Moreover, it is shown that the activity resetting mechanism elicited by electrical stimulation provides a natural explanation to the ineffectiveness of irregular (i.e., aperiodic) stimulation patterns, which has been commonly observed in previously reported pathophysiology models of Parkinson's disease.

December 29, 2017

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Structure of PINK1 and mechanisms of Parkinson's disease... - eLife

December 21, 2017
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Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments. Panchanan MaitiEmail author,; Jayeeta Manna and; Gary L. DunbarEmail author. Translational Neurodegeneration20176:28. https://doi.org/10.1186/s40035-017-0099-z. © The Author(s). 2017. Received: 16 May .

December 23, 2017
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14 Jun 2011. α-synuclein (aS) is a natively unfolded pre-synaptic protein found in all Parkinson's disease patients as the major component of fibrillar plaques. Metal ions, and especially Cu(II), have been demonstrated to accelerate aggregation of aS into fibrillar plaques, the precursors to Lewy bodies. In this work .

December 25, 2017
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16 Aug 2017. Moreover, it is shown that the activity resetting mechanism elicited by electrical stimulation provides a natural explanation to the ineffectiveness of irregular (i.e., aperiodic) stimulation patterns, which has been commonly observed in previously reported pathophysiology models of Parkinson's disease.

December 24, 2017

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Structure of PINK1 and mechanisms of Parkinson's disease... - eLife

January 18, 2018

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Mechanisms behind sensory deficits in Parkinson's disease | News...

January 21, 2018
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Mechanisms in Parkinson's Disease - Models and... - InTechOpen

January 23, 2018
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Abstract. Previous research on cognitive set shifting in patients with Parkinson's disease has often been confounded by concept formation, rule learning, working memory and/or general slowing of cognitive processes. To circumvent this problem, the present study used the task-set switching procedure in which good .

January 19, 2018
Abstract. The power of placebos has long been recognized for improving numerous medical conditions such as Parkinson's disease (PD). Little is known, however, about the mechanism underlying the placebo effect. Using the ability of endogenous dopamine to compete for [11C]raclopride binding as measured by positron . i3
Expectation and Dopamine Release: Mechanism of the Placebo...

January 16, 2018

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Mechanisms behind sensory deficits in Parkinson's disease | News...

January 24, 2018
Parkinson's disease (PD) results primarily from the death of dopaminergic neurons in the substantia nigra. Current PD medications treat symptoms; none halt or retard dopaminergic neuron degeneration. The main obstacle to developing neuroprotective therapies is a limited understanding of the key molecular mechanisms . i5
Mechanisms in Parkinson's Disease - Models and... - InTechOpen

January 17, 2018
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Mechanisms of cognitive set flexibility in Parkinson's disease | Brain...

January 22, 2018
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Abstract. The power of placebos has long been recognized for improving numerous medical conditions such as Parkinson's disease (PD). Little is known, however, about the mechanism underlying the placebo effect. Using the ability of endogenous dopamine to compete for [11C]raclopride binding as measured by positron .

January 25, 2018

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Mechanisms behind sensory deficits in Parkinson's disease | News...

February 16, 2018

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Deep Brain Stimulation for Parkinson Disease: Overview...

February 19, 2018
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19 Apr 2016. Human LRRK2 (Leucine-Rich Repeat Kinase 2) has been associated with both familial and idiopathic Parkinson's disease (PD). Although several LRRK2 mediated pathways and interaction partners have been identified, the cellular functions of LRRK2 and LRRK2 mediated progression of PD are still only .

February 21, 2018
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Mechanisms of Gene-Environment Interactions in Parkinson's Disease

February 20, 2018

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Masked Faces in Parkinson Disease: Mechanism and Treatment...


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Generic Stalevo

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LEVODOPA is converted to a chemical called dopamine (DOE pa meen) in the brain. Symptoms of Parkinson's disease may be caused by low levels of dopamine in the brain. CARBIDOPA helps prevent the breakdown of levodopa before it can reach the brain and take effect. ENTACAPONE increases levels of levodopa in the body. The combination of carbidopa, entacapone, and levodopa is used to treat Parkinson symptoms such as muscle stiffness, tremors, spasms, and poor muscle control.

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Generic Artane

Generic Artane

Generic Artane is used to treat Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced.

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Generic Mirapex

Generic Mirapex

Generic Mirapex has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease. Pramipexole tablets are used to treat signs and symptoms of Parkinson's disease and for the treatment of Restless Legs Syndrome (RLS)

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Generic Motilium

Generic Motilium

Generic Motilium is a medicine that increases the movements or contractions of the stomach and bowel. It is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease.

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Generic Stalevo

Generic Stalevo

LEVODOPA is converted to a chemical called dopamine (DOE pa meen) in the brain. Symptoms of Parkinson's disease may be caused by low levels of dopamine in the brain. CARBIDOPA helps prevent the breakdown of levodopa before it can reach the brain and take effect. ENTACAPONE increases levels of levodopa in the body. The combination of carbidopa, entacapone, and levodopa is used to treat Parkinson symptoms such as muscle stiffness, tremors, spasms, and poor muscle control.

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Generic Symmetrel

Generic Symmetrel

Generic Symmetrel is an antiviral. It is used to prevent or treat certain influenza (flu) infections (type A). It may be given alone or along with flu shots. Generic Symmetrel will not work for colds, other types of flu or other virus infections. This medicine is also used to treat Parkinson's disease and other movement disorders.

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